Includes micelles of nano-sized are embedded in a water-soluble carrier and then, include low solubility chemicals, such as a biologically active material dissolved in the auxiliary material, the present invention, the solid thermal stability relates to a composition. The invention further relates to a process for the preparation of pharmaceutical forms of preparation of solid compositions of the thermal stability and comprising the same. [Selection] Figure Figure 1本発明は、補助物質中に溶解された生物学的活性物質のような低溶解性化学物質を含み、そして水溶性担体中に包埋されているナノサイズのミセルを含む、熱安定性の固形組成物に関する。本発明は更に、熱安定性の固形組成物の調製法および同を含んでなる製薬学的剤形の調製法に関する。【選択図】図1