Paladin Labs Inc.;Paladin Labs Europe Limited;Paladin Labs (Barbados) Inc.
发明人:
申请号：
EP05815074.9
公开号：
EP1817035B1
申请日:
2005.11.28
申请国别(地区):
EP
年份:
2019
代理人:
摘要：
The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent； particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product； particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.
