Dean J. Naylor;Linda A. Ward;Inge E. A. Flesch;Barbara J. Johnson;Caroline A. Dobbin;Christopher B. Howard
发明人:
Barbara J. Johnson,Caroline A. Dobbin,Dean J. Naylor,Linda A. Ward,Inge E. A. Flesch,Christopher B. Howard
申请号:
US11995524
公开号:
US09457062B2
申请日:
2006.07.11
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to methods for modulating Toll-like receptor signalling in a subject, or in at least one cell, tissue or organ thereof, methods for treating or preventing a disease or condition in a subject, methods for modulating the production and/or secretion of one or more immunomodulators in a subject, or at least one cell, tissue or organ thereof, wherein said methods involve the administration of chaperonin 10, and wherein the chaperonin 10 associates with a Toll-like receptor in an activation cluster. Also contemplated are associated compositions and uses thereof.