Spicer, Julie Ann,Denny, William Alexander,Miller, Christian Karl,O'Connor, Patrick David,Huttunen, Kristiina,Trapani, Joseph A.,Hill, Geoff,Alexander, Kylie,OConnor, Patrick David
申请号：
AU2013305475
公开号：
AU2013305475B2
申请日:
2013.08.21
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Compounds of formula (la) and pharmaceutically acceptable salts, solvates, and hydrates thereof and related methods of modulatin perforin activity on a cell: wherein Ring A is selected from a 6-10 membered aryl, 5-6 membered cycloalkyi, 5-6 membered heteroaryl or 5-6 membered heterocyclyl, wherein the heteroaryl and heterocyclyl rings comprise at least one heteroatom selected from N, O or S； and wherein the aryl, cycloalkyi, heteroaryl or heterocyclyl rings are optionally substituted with 1 to 3 substituents selected from halo, nitro, -C
