PURPOSE: A microalgae fermentation is provided to enhance antioxidation by fermenting Haptophyceae with Hansenula polymorpha. CONSTITUTION: A microalgae fermentation is prepared by fermenting Haptophyceae with Hansenula polymorpha and freeze-drying the fermented microalgae. The microalgae fermentation has an antioxidative activity in vivo. A pharmaceutical composition with an antioxidative activity contains 0.01-99 wt% of the microalgae fermentation as an active ingredient. A health functional composition with an antioxidative activity contains the microalgae fermentation as an active ingredient. [Reference numerals] (AA) Scavenging activity(%)； (BB) Concentration(mg/mL)본 발명은 미세조류를 효모에 의해 발효시켜 그의 물질 조성 및 아미노산 조성을 변화시킴으로써 항산화 특성을 증가시킨 것을 특징으로 하는 미세조류 발효물 및 그의 항산화 용도에 관한 것이다.
