LEVY, JOHN, P.,REED, REBECCA, A,MCNULTY, JOSEPH,JOHNSON, ROBERT, G
申请号：
PH12015502095
公开号：
PH12015502095A1
申请日:
2015.09.14
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
