Levy, John P.,Reed, Rebecca A.,McNulty, Joseph,Johnson, Robert G.
申请号：
AU2014236086
公开号：
AU2014236086A1
申请日:
2014.03.14
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles.
