ANDREWS, STEVEN W.,ARONOW, SEAN,BLAKE, JAMES F.,BRANDHUBER, BARBARA J.,COOK, ADAM,HAAS, JULIA,JIANG, YUTONG,KOLAKOWSKI, GABRIELLE R.,MCFADDIN, ELIZABETH A.,MCKENNEY, MEGAN L.,MCNULTY, OREN T.,METCALF,
申请号：
CA3039760
公开号：
CA3039760A1
申请日:
2017.10.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Provided herein are compounds of the Formula I and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
