ANDREWS, Steven W.,ARONOW, Sean,BLAKE, James F.,BRANDHUBER, Barbara J.,COOK, Adam,HAAS, Julia,JIANG, Yutong,KOLAKOWSKI, Gabrielle R.,MCFADDIN, Elizabeth A.,MCKENNEY, Megan L.,MCNULTY, Oren T.,METCALF,
申请号：
PH12019500775
公开号：
PH12019500775A1
申请日:
2019.04.10
申请国别(地区):
PH
年份:
2019
代理人:
摘要：
Provided herein are compounds of the Formula I and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
