Steven W. ANDREWS,Sean ARONOW,James F. BLAKE,Barbara J. BRANDHUBER,James COLLIER,Adam COOK,Julia HAAS,Yutong JIANG,Gabrielle R. KOLAKOWSKI,Elizabeth A. McFADDIN,Megan L. McKENNEY,Oren T. McNULTY,Andre
申请号：
US16579150
公开号：
US20200030311A1
申请日:
2019.09.23
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are compounds of the Formula I:or pharmaceutically acceptable salt or solvate thereof, wherein A, B, X1, X2, X3, X4, Ring D, E, Ra, Rb, n and m have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.
