WALLS, SHANE M.,REN, LI,RAMANN, GINELLE A.,MORENO, DAVID A.,METCALF, ANDREW T.,MCFADDIN, ELIZABETH A.,KOLAKOWSKI, GABRIELLE R.,BLAKE, JAMES F.,DAI, DONGHUA,HAAS, JULIA,JIANG, YUTONG,KAHN, DEAN
申请号:
CA3087972
公开号:
CA3087972A1
申请日:
2019.01.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Provided herein are compounds of the Formula I: and tautomers and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2 and R3 have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.