BOYS MARK LAURENCE,BURGESS LAURENCE E,GRONEBERG ROBERT D,HARVEY DARREN M,HUANG LILY,KERCHER TIMOTHY,KRASER CHRISTOPHER F,LAIRD ELLEN,TARLTON EUGENE,ZHAO QIAN
申请号:
IN3485/KOLNP/2012
公开号:
IN2012KN03485A
申请日:
2012.11.12
申请国别(地区):
IN
年份:
2013
代理人:
摘要:
Compounds of Formula I: (Formula should be inserted here) and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R1, R2, R3, R4, R5, R6, R7, X1 and X2 have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.