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5, 7-substituted-imidazo [1, 2-c] pyrimidines as inhibitors of JAK kinases
专利权人:
Array BioPharma Inc.
发明人:
Boys, Mark Laurence,Burgess, Laurence E.,Groneberg, Robert D.,Harvey, Darren M.,Huang, Lily,Kercher, Timothy,Kraser, Christopher F.,Laird, Ellen,Tarlton, Eugene,Zhao, Qian
申请号:
AU2011240808
公开号:
AU2011240808A1
申请日:
2011.04.11
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Compounds of Formula I: (Formula should be inserted here) and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R, R, R, R, R, R, R, X and X have the meanings given in the specification, are inhibitors of one or more JAK kinases and are useful in the treatment of autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, as well as hematologic disorders and malignancies and their co-morbidities.
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