ALLEN SHELLEY,BOYS MARK LAURENCE,CHICARELLI MARK J,FELL JAY BRADFORD,FISCHER JOHN P,GAUDINO JOHN,HICKEN ERIK JAMES,HINKLIN RONALD JAY,KRASER CHRISTOPHER F,LAIRD ELLEN,ROBINSON JOHN E,TANG TONY P,BURGE
申请号:
IN201737023646
公开号:
IN201737023646A
申请日:
2017.07.05
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Compounds of Formula I: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which R R R and R have the meanings given in the specification are inhibitors of one or more JAK kinases and are useful in the treatment of JAK kinase associated diseases and disorders such as autoimmune diseases inflammatory diseases rejection of transplanted organs tissues and cells as well as hematologic disorders and malignancies and their co morbidities.