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N-heteroaryl compounds with cyclic bridge unit for the treatment of parasitic diseases
- 专利权人:
- Intervet International B.V.
- 发明人:
- BERGER, Michael,KERN, Christopher,ECK, Marko,SCHRÖDER, Jörg
- 申请号：
- ES11761594
- 公开号：
- ES2624845T3
- 申请日:
- 2011.09.28
- 申请国别(地区):
- ES
- 年份:
- 2017
- 代理人:
- 摘要：
- A compound of the formula (I) and pharmaceutically acceptable solvates, N-oxides and salts thereof, ** Formula ** in which R1 is halogen, amino, C1-C6 alkylamino, di- (C1-C6 alkyl) amino , C1-C6 alkylamino-C1-C6 alkyl, di- (C1-C6 alkyl) amino C1-C6 alkyl, C1-C6 alkyl, hydroxy-C1-C6 alkyl, C1-C6 alkyloxy, C1-C6 alkylthio, C2 alkenyl -C6, C2-C6 alkynyl, C1-C6 alkyloxy-C1-C6 alkyl, C1-C6 alkylthio-C1-C6 alkyl, C1-C6 alkylcarbonyl, C2-C6 alkenylcarbonyl, SF5, C1-C6 alkylsulfonyl, wherein each of the carbon-containing radicals is optionally substituted with one or more halogen atoms, preferably fluorine atoms, R2 is hydrogen, halogen, amino, C1-C6 alkylamino, di- (C1-C6 alkyl) amino, C1-C6 alkylamino-C1-C6 alkyl, di- (C1-C6 alkyl) amino C1-C6 alkyl, C1-C6 alkyl, hydroxy-C1-C6 alkyl, C1-C6 alkyloxy, C1-C6 alkylthio, C2 alkenyl C6, C2-C6 alkynyl, C1-C6 alkyloxy-C1-C6 alkyl, C1-C6 alkylthio -C1-C6 alkyl, C1-C6 alkylcarbonyl, C1-C6 alkyloxycarbonyl, C2-C6 alkenylcarbonyl, wherein each of the carbon-containing radicals is optionally substituted with one or more halogen atoms, preferably fluorine atoms, preferably R2 is hydrogen, R3 is hydrogen, C1-C6 alkyl or cycloalkyl, preferably hydrogen, R4 is hydrogen, C1-C6 alkyl or cycloalkyl, preferably hydrogen, R5 is hydrogen, C1-C6 alkyl or cycloalkyl, R6 is hydrogen, C1-C6 alkyl , cycloalkyl, hydroxy, C1-C6 alkyloxy, C1-C6 phenylalkyl, C1-C6 hydroxyalkyl, C1-C6 alkyloxy-C1-C6 alkyl, phenylalkyl-C1-C6-C1-C6 alkyl, C1-C6 thiolalkyl, C1-C6 alkylthio- C1-C6 alkyl, phenylalkyl-C1-C6-alkyl C1-C6, hydroxycarbonyl, hydroxycarbonylalkyl C1-C6, alkyloxycarbonyl C1-C6, alkyloxycarbonyl C1-C6-alkyl C1-C6, aminocarbonyl, aminocarbonylalkyl C1-C6, alkylaminocarbonyl C1-C6 alkyl C1-C6- (C1-C6 alkyl), di (C1-C6 alkyl) amino carbonyl, di (C1-C6 alkyl) aminocarbonyl (C1-C6 alkyl), C1-C6 alkylamino-C1-C6 alkyl, di (C1-C6 alkyl-C1-C6 amino alkyl, phenyl, C1-C6 phenylalkyl, wherein each phenyl group is optionally substituted with hydroxy, alkyloxy or
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
