Refers to certain N - heteroaryl compounds which are useful as Drugs, in general, More specifically as Medicines for Animals. The Medicine can preferably be used for the treatment of helminthic Infections and parasites, such as caused by helminth infections.Also refers to use of the compounds for preparing Medicines and treatments that include the Administration of the compounds to Animals in need of such treatment. It also relates to the preparation of the compounds of N - heteroaryl. It also relates to pharmaceutical compositions and Kits comprising the compounds.Claim 1: a compound of the formula (1) and their n-oxides, solvates and pharmaceutically acceptable Salts and prodrugs, where R1 is alkyl halide, Amine, C1 - 6 - amino -, di (alkyl amino alkyl C1, C1 - 6) - 6 - amino alkyl di - (C1 - 6 C1 - 6) alkyl amino alkyl alkyl C1 C1 - 6, 6 -, hydroxy - alq Uilo C1 - 6 - 6 Alquiltio alquiloxi, C1, C1 - C2 - alquenilo 6, 6, 6 alquinilo alquiloxi C1 C2, C1 - alkyl - 6 6Alquiltio C1 C1 - 6 - 6 - alkyl, alkyl carbonyl alquiloxi C1 - 6, 6 - C1 - C2 carbonyl, carbonyl alquenilo - 6, 6 - C1 - sedan, alkyl sulfonyl where every radical containing carbon is optionally substituted with one or more Atoms of halogen, preferably Fluorine Atoms； R2 is Hydrogen, halogen, alkyl Amine, C1 - 6 - amino -, di (alkyl amino alkyl C1, C1 - 6) - 6 - amino alkyl C1 - 6Di - (alkyl C1 - 6) amino alkyl C1 C1 - 6 - 6, alkyl, Hydroxy alkyl C1 - 6 - 6 Alquiltio alquiloxi, C1, C1 - C2 - alquenilo 6, 6, 6 alquinilo alquiloxi C1 C2, C1 - alkyl - 6 - 6, 6 - alkyl - Alquiltio C1 C1 - 6, 6 - alkyl carbonyl alquiloxi C1, C1 - C2 - 6 - alquenilo carbonyl, carbonyl, where each of the lies Les containing carbon is optionally substituted with one or more Atoms of halogenPreferably Fluorine ATOMS, preferably R2 is Hydrogen； R3 is Hydrogen, alkyl or cycloalkyl C1 - 6, preferably Hydrogen； R4 is Hydrogen, alkyl or cycloalkyl C1 - 6, preferably Hydrogen； R5 is Hydrogen, alkyl or cycloalkyl C1 - 6； R6 is Hydrogen
