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N-heteroaryl compounds
专利权人:
Intervet International B.V.
发明人:
BERGER, Michael,KERN, Christopher,ECK, Marko,SCHRÖDER, Jörg
申请号:
ES11761595
公开号:
ES2622881T3
申请日:
2011.09.28
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
A compound of formula (I) and pharmaceutically acceptable salts, solvates, N-oxides ** Formula ** wherein R1 is halogen, C1-C6 alkyl, C1-C6 alkyloxy, C1-C6 alkylthio, C2-C6 alkenyl, alkynyl C2-C6, C1-C6 alkyloxy C1-C6 alkyl, C1-C6 alkylthio C1-C6 alkyl, C1-C6 alkylcarbonyl, C2-C6 alkenyl carbonyl, SF5, C1-C6 alkyl sulfonyl, where each of the radicals containing Carbon is optionally substituted with one or more halogen atoms, preferably fluorine atoms, R2 is hydrogen, halogen, C1-C6 alkyl, C1-C6 alkyloxy, C1-C6 alkylthio, C2-C6 alkenyl, C2-C6 alkynyl, C1 alkyloxy -C6 C1-C6 alkyl, C1-C6 alkyl C1-C6 alkyl, C1-C6 alkyl carbonyl, C2-C6 alkenyl carbonyl, where each of the carbon-containing radicals is optionally substituted with one or more halogen atoms, preferably atoms of fluorine, R3 is hydrogen, C1-C6 alkyl or cycloalkyl, preferably hydrogen, R4 is hydrogen, C1-C6 alkyl or cycloalkyl, preferably Only hydrogen, R5 is hydrogen, C1-C6 alkyl, cycloalkyl, acyl, cycloalkyloxycarbonyl or C1-C6 alkyl oxycarbonyl, R6 is hydrogen, C1-C6 alkyl, cycloalkyl, hydroxy, C1-C6 alkyloxy, phenylalkyl C1-C6 alkyl, hydroxy C1- C6, C1-C6 alkyloxy C1-C6 alkyl, phenylalkyl C1-C6 alkyl C1-C6 alkyl, thiol C1-C6 alkyl, C1-C6 alkylthio C1-C6 alkyl, phenyl C1-C6 alkylthio C1-C6 alkyl, hydroxycarbonyl, hydroxycarbonyl C1 alkyl -C6, C1-C6 alkyloxycarbonyl, C1-C6 alkyloxycarbonyl C1-C6 alkyl, aminocarbonyl, aminocarbonyl C1-C6 alkyl, C1-C6 alkylaminocarbonyl, C1-C6 alkylaminocarbonyl, di (C1-C6 alkyl) aminocarbonyl, di (C1-C6 alkyl) aminocarbonyl (C1-C6 alkyl), C1-C6 alkylamino C1-C6 alkyl, di (C1-C6 alkyl) amino C1-C6 alkyl, phenyl, phenyl C1-C6 alkyl, where the phenyl group is optionally substituted with hydroxy, cycloalkyloxy or C1-C6 alkyloxy, R7 is hydrogen, C1-C6 alkyl or cycloalkyl, or R6 is joined together with R8 to form an alkyl group C 1 -C 3 and R 7 lene binds together with R 9 to form a C 1 -C 3 alkylene group, wherein one or both of said C 1 -C 3 alkylene groups are optionally substit
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