The drug is best used to treat worm infections and parasitic diseases, such as worm infections. It also involves the use of compounds for drugs and treatment, including for animals in need of such treatment. It also refers to n-propene compounds and their preparation, as well as pharmaceutical compounds and tool kits containing compound 1: a formula compound (1) and its salts, solutions, N-oxides or acceptable halogens on drugs, C1-6 tar, C1-6 tar and other acceptable Prof compounds on drugs,C1-6 alkylthio, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkyloxy-C1-6 alkyl, C1-6 alkylthio-C1-6 alkyl, C1-6-carbonyl alkyl, C2-6-carbonyl alkenyl, SF5 , C1-6-sulfonyl alkyl where each of the carbon-containing radicals is optionally substituted with one or more halogen atoms, preferably fluorine atoms； R2 is hydrogen, halogen, C1-6 alkyl, C1-6 alkyloxy, C1-6 alkylthio, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkyloxy- C1-6 alkyl, C1-6 alkylthio-C1-6 alkyl , C 1-6 alkylcarbonyl, C 2-6 alkenyl carbonyl, C 2-6 alkenyl carbonyl,where each of the carbon-containing radicals is optionally substituted with one or more halogen atoms, preferably fluorine atoms； R3 is hydrogen, C1-6 alkyl or cycloalkyl, preferably hydrogen； R4 is hydrogen, C1-6 alkyl or cycloalkyl, preferably hydrogen； R 5 is hydrogen, C 1-6 alkyl, cycloalkyl, acyl, cycloalkyloxycarbonyl, C 1-6 alkyloxycarbonyl； R6 is hydrogen, C1-6 alkyl, cycloalkyl, hydroxy, C1-6 alkyloxy, phenyl-C1-6 alkyloxy, hydroxy-C1-6 alkyl, C1-6 alkyloxy-C1-6 alkyl, phenyl-C1-6 alkyloxy C1-6, thiol-C1-6 alkyl, C1-6 alkylthio-C1-6 alkyl, phenyl-C1-6 alkylthio-C1-6 alkyl, hydroxycarbonyl,hydroxycarbonyl-C1-6 alkyl, C1-6 alkyloxycarbonyl, C1-6 alkyloxy-C1-6 alkyl, aminocarbonyl, aminocarbonyl-C1-6 alkyl, C1-6-aminocarbonyl alkyl, C1-6-aminocarbonyl-alkyl C1-6, di (C1-6 alkyl) aminocarbonyl, di (C1-6 alkyl) aminocarbonyl-C1-6 alkyl, C1-6 alkyl-C1-6 alkyl, di (C1-6 alkyl) amino-C1 alkyl -6, phenyl, phenyl-C 1-6 alkyl, where each phenyl group is optionally substitute
