This invention includes the porous bio glass and the powdered calcium sulfate - hydrate of powdered or granulation condition, it regards the constituent for the bone substitute. This invention, relates, to also the injection possible constituent in order in addition to form the bone substitute, the said constituent, 10 - 50 mass which is added % the water and the porous bio glass of powdered or granulation condition and as the description above which consists of the powdered calcium sulfate - hydrate includes the constituent.本発明は、粉末状又は顆粒状の多孔質バイオガラス及び粉末状の硫酸カルシウムα-半水和物を含む、骨代替物用の組成物に関する。本発明は、また骨代替物を形成するための、注入可能な組成物にも係り、該組成物は、添加された10~50質量%の水と、粉末状又は顆粒状の多孔質バイオガラス及び粉末状の硫酸カルシウムα-半水和物で構成される上記の如き組成物を含む。