NIMJEE, Shahid, M.,PITOC, George, A.,LAYZER, Juliana,SULLENGER, Bruce
申请号:
EP17851722
公开号:
EP3512526A4
申请日:
2017.09.18
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.