Shahid M. NIMJEE,George A. PITOC,Juliana LAYZER,Bruce SULLENGER
申请号：
US16334307
公开号：
US20190218553A1
申请日:
2017.09.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
