AGENTS CIBLANT LE FACTEUR DE VON WILLEBRAND (VWF) ET LEURS PROCÉDÉS D'UTILISATION

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专利权人:

Duke University;Ohio State Innovation Foundation

发明人:

申请号：

EP17851722.3

公开号：

EP3512526A4

申请日:

2017.09.18

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.

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