Johannes, Antonius, HEEMSKERK,Judith, Christina, Theodora, VAN DEUTEKOM,Petra, VAN KUIK-ROMEIJN,Gerard, Johannes ,PLATENBURG
申请号:
IL220979
公开号:
IL220979A
申请日:
2012.07.16
申请国别(地区):
IL
年份:
2012
代理人:
摘要:
The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.