Gerard Johannes Platenburg;Johannes Antonius Heemskerk;Petra Van Kuik-Romeijn;Judith Christina Theodora Van Deutekom
发明人:
Johannes Antonius Heemskerk,Judith Christina Theodora Van Deutekom,Petra Van Kuik-Romeijn,Gerard Johannes Platenburg
申请号:
US13568866
公开号:
US20120322724A1
申请日:
2012.08.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.