HEEMSKERK, JOHANNES ANTONIUS,VAN DEUTEKOM, JUDITH C. T.,VAN KUIK-ROMEIJN, PETRA,PLATENBURG, GERARD JOHANNES
申请号:
CA2942716
公开号:
CA2942716C
申请日:
2008.07.14
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.