HEEMSKERK, JOHANNES ANTONIUS,VAN DEUTEKOM, JUDITH CHRISTINA THEODORA,VAN KUIK-ROMEIJN, PETRA,PLATENBURG, GERARD JOHANNES
申请号:
CA2693048
公开号:
CA2693048C
申请日:
2008.07.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The invention provides conjugates, comprising an organ, tissue or tumor cellhoming molecule linked to a moiety.Such a moiety can be, for example, an oligonucleotide, small interfering RNA,gene, virus, protein, pharmaceutical or detectableagent. In addition the invention provides methods to diagnose or treat apathology of the muscle or heart, by administrating to asubject having or suspected of having a pathology a molecule or conjugate thathomes to, binds to and is taken up by the musclecells or heart cells.