GERARD JOHANNES PLATENBURG;JOHANNES ANTONIUS HEEMSKERK;PROSENSA TECHNOLOGIES B.V.;PETRA VAN KUIK-ROMEIJN;JUDITH CHRISTINA THEODORA VAN DEUTEKOM
发明人:
JOHANNES ANTONIUS HEEMSKERK,JUDITH CHRISTINA THEODORA VAN DEUTEKOM,PETRA VAN KUIK-ROMEIJN,GERARD JOHANNES PLATENBURG
申请号:
IL20327310
公开号:
IL203273A
申请日:
2010.01.12
申请国别(地区):
IL
年份:
2014
代理人:
摘要:
The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.