Molecules for targeting compounds at different selected organs or tissues

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专利权人:

BioMarin Technologies B.V.;Academisch Ziekenhuis Leiden

发明人:

HEEMSKERK, Johannes, Antonius,VAN DEUTEKOM, Judith, Christina, Theodora,VAN KUIK-ROMEIJN, Petra,PLATENBURG, Gerardus, Johannes

申请号：

DK08779023

公开号：

DK2167136T3

申请日:

2008.07.14

申请国别(地区):

DK

年份:

2016

代理人:

摘要：

The invention provides conjugates, comprising an organ, tissue or tumor cell homing molecule linked to a moiety. Such a moiety can be, for example, an oligonucleotide, small interfering RNA, gene, virus, protein, pharmaceutical or detectable agent. In addition the invention provides methods to diagnose or treat a pathology of the muscle or heart, by administrating to a subject having or suspected of having a pathology a molecule or conjugate that homes to, binds to and is taken up by the muscle cells or heart cells.

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