METHOD FOR DIAGNOSING CANCERS EXPRESSING THE HER2 RECEPTOR OR ITS TRUNCATED VARIANTS

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专利权人:

FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA I ESTUDIS AVANCATS (ICREA);FUNDACIO PRIVADA INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL HEBRON;FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONOCOLOGICA V

发明人:

ARRIBAS LOPEZ JOAQUIN,PEDERSEN KIM,ANGELLINI PIER-DAVIDE,PARRA PALAU JOSEP LLUIS,LAOS SIRLE,BASELGA TORRES JOSE

申请号：

ZA201009010

公开号：

ZA201009010B

申请日:

2010.12.14

申请国别(地区):

ZA

年份:

2012

代理人:

摘要：

The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/