Method for diagnosing cancers expressing the HER2 receptor or its truncated variants

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专利权人:

Fundacio Privada Institut d'Investigacio Oncologica de Vall Hebron;Fundacio Privada Institut de Recerca Hospital Universitari Vall He;Fundacio Privada Institucio Catalana de Recerca i Estudis Avancats

发明人:

Arribas Lopez, Joaquin,Pedersen, Kim,Angellini, Pier-Davide,Parra Palau, Josep Lluis,Laos, Sirle,Baselga Torres, Jose

申请号：

AU2015202854

公开号：

AU2015202854A1

申请日:

2015.05.26

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

#$%^&*AU2015202854A120150618.pdf#####ABSTRACT The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognises an epitope of a HER2 receptor truncated form, said epitope being 5 defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ JD NO: 1 in a patient sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/