FUNDACIO PRIVADA INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL HEBRON;FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA IESTUDIS AVANCATS (ICREA);FUNDACIO PRIVADA INSTITUT D'INVESTIGACIO ONCOLOGICA DE
发明人:
申请号:
IL20976910
公开号:
IL209769A
申请日:
2010.12.05
申请国别(地区):
IL
年份:
2016
代理人:
摘要:
The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.