method for diagnosing cancers expressing the her2 receptor or its truncated variants

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专利权人:

FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCOLÓGICA DE VALL HEBRON;FUNDACIÓ PRIVADA INSTITUCIÓ CATALANA DE RECERCA IESTUDIS AVANCATS;FUNDACIÓ PRIVADA INSTITUT DE RECERCA HOSPITAL UNIVERSITARI VALL HEB

发明人:

JOAQUÍN ARRIBAS LÓPEZ,JOSEP LLUIS PARRA PALAU,JOSÉ BASELGA TORRES,KIM PEDERSEN,PIER-DAVIDE ANGELLINI,SIRLE LAOS

申请号：

BRPI0914969

公开号：

BRPI0914969A2

申请日:

2009.06.05

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor. The invention provides antibodies or fragments thereof that recognizes an epitope of a HER2 receptor truncated form, said epitope being defined by a sequence included in SEQ ID NO: 2. The invention also provides a method of cancer diagnosis, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/