DERIVADOS DE ANILINA, SU PREPARACIÓN Y SU APLICACIÓN TERAPÉUTICA.

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专利权人:

SANOFI

发明人:

David MIDDLEMISS,John FEUTRILL,Caroline LERICHE

申请号：

MX2014003206

公开号：

MX347855B

申请日:

2012.09.07

申请国别(地区):

MX

年份:

2017

代理人:

摘要：

The present invention relates to aniline derivatives of formula (I), to their preparation and to their therapeutic application, for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN； R1b represents H, an halogen or a (C1-C6)alkyl； R1c represents H or a(C1-C6)alkyl； R2 represents H, an halogen, an OH, an O-(C1-C6)alkyl or (C1-C6)alkyl； R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O-(C1-C6)alkyl, a CONH2 or CN； R4 represents H, an halogen or a (C1-C6)alkyl； R5 represents H or F: R7 represents H or F； R8 represents H or F； R9 represents H or (C1-C6)alkyl, or one of its enantiomers.La presente invención se refiere a derivados de anilina, su preparación y su aplicación terapéutica.

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