ANILINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

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专利权人:

发明人:

John FEUTRILL,Caroline LERICHE,David MIDDLEMISS

申请号：

US14968423

公开号：

US20160199330A1

申请日:

2015.12.14

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to therapeutic applications of aniline derivatives of formula (I), for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN R1b represents H, an halogen or a (C1-C6)alkyl R1c represents H or a (C1-C6)alkyl R2 represents H, an halogen, an OH, an O—(C1-C6)alkyl or (C1-C6)alkyl R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O—(C1-C6)alkyl, a CONH2 or CN R4 represents H, an halogen or a (C1-C6)alkyl R5 represents H or F: R7 represents H or F R8 represents H or F R9 represents H or (C1-C6)alkyl, or one of its enantiomers.

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