DE MICO, ANTONELLA,COTTARELLI, ANDREA,FUGGETTA, MARIAPIA,LANZILLI, GIULIA,TRICARICO, MARIA
申请号：
AT07736845
公开号：
AT540946T
申请日:
2007.05.10
申请国别(地区):
AT
年份:
2012
代理人:
摘要：
The invention relates to dioxaspiroketal derivatives of formula (I): wherein R, is selected from the group consisting of H, straight or branched chain C1-C6 alkyl, C1-C6 alkoxy, C2-C6 alkenyl, cycloalkyl, heterocyclyl, phenyl, optionally para-, meta- or ortho-substituted with 0 to 3 substituent selected from halogen, &mdash；CN, &mdash；NH2, &mdash；OH, &mdash；NO2, COOR2, wherein R2 is selected from H and C1-C6 alkyl, n is 1 or 2, X is O or S, R1 is selected from H, OH, halogen, C1-C6 alkyl, C1-C6 alkoxy, COOR3, wherein R3 is selected from H and C1-C6 alkyl, or physiologically acceptable salts thereof, process for preparation thereof, their uses in medical field, in particular as anti-tumor medicaments.
