The present disclosure relates to aniline derivatives of formula (I), to their preparation and to their therapeutic application, for example in treating glaucoma: Formula (I), R1a represents H, an halogen, a (C1-C6)alkyl or a CN R1b represents H, an halogen or a (C1-C6)alkyl R1c represents H or a(C1-C6)alkyl R2 represents H, an halogen, an OH, an O-(C1-C6)alkyl or (C1-C6)alkyl R3 represents H, an halogen, a (C1-C6)alkyl, an OH, an O-(C1-C6)alkyl, a CONH2 or CN R4 represents H, an halogen or a (C1-C6)alkyl R5 represents H or F: R7 represents H or F R8 represents H or F R9 represents H or (C1-C)alkyl, or one of its enantiomers.