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Quinoline or quinoxaline derivatives for treating neurodegenerative diseases
专利权人:
Fanny Schmidt
发明人:
Fanny Schmidt,Bruno Figadere,Sylvia Rita Vozari,Pierre Champy,Xavier Franck
申请号:
US13003992
公开号:
US08445511B2
申请日:
2009.07.20
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compounds of Formula (I) below, to their pharmaceutically acceptable salts and to their isomers or mixtures of isomers: HetAr—X—CHR1R2 (I) in which: —HetAr represents a group chosen from: —X represents a linear, saturated or unsaturated, hydrocarbon-based chain comprising from 8 to 22 carbon atoms, optionally interrupted by an —NH— or —NH—CO— group, —R1 represents a hydrogen atom or an —OH, —O(C1-C6)alkyl, —OCO((C1-C6)alkyl), —OSO2((C1-C6)alkyl) or —OSO3H group, and —R2 represents a hydrogen atom or a (C2-C6)alkynyl, (C2-C6)alkenyl or (C3-C6)cycloalkyl group. The present invention also relates to a process for preparing the compounds of Formula (I), and also to the use thereof, especially in the treatment of neurodegenerative diseases.
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