REID LOLA M.,LOZOYA OSWALDO,TURNER RACHAEL,GERBER DAVID
申请号：
ARP110101582
公开号：
AR081906A1
申请日:
2011.05.06
申请国别(地区):
AR
年份:
2012
代理人:
摘要：
Claim 1: a method of transplanting cells from internal organs to objects with disease or dysfunction of internal organs, including (a) obtaining normal cells from internal organs of donors； (b) Combining cells with one or more gelatinous biomaterials to form a mixture； (c) optionally combining the mixture with a nutrient medium, a signaling molecule, an outer matrix protein, or both； (d) introducing a step mixture (b) to the subject,In (d) Paso implanted cells, a large part of them will live in or at least live in one part of the living organ in vivo 2: method required in Item 1, in which normal cells are stem cells, forced parents or mature cells. Claim 7: the methodology described in claim 1, in which the donor is a non autistic donor. Claim 9: the method in claim 1, i.e. the increased cells include blood vessels, endocrine cells, star cell precursors, star cells, female cells, and epithelial stem cells,mature parenchymal cells or combinations thereof. Claim 10: The method according to claim 1, wherein said one or more biomaterials comprise collagens, laminins, adhesion molecules, proteoglycans, hyaluronans, glucosaminoglycan chains, chitosan, alginate and synthetic, biodegradable and biocompatible polymers, or combinations of the same. Claim 11: The method according to claim 1, wherein the signaling molecules comprise fibroblast growth factor, hepatocyte growth factor, epidermal growth factor,Vascular endocrine cell growth factor (VEGF),Insulin type I growth factor, insulin type II growth factor (IGF-II),Tumor-m, LIF,Interlequines, transforming-b (TGF-b) growth factor,HGF, transferrina, insulin, transferrina / Fe, tri iodotrronirina, T3, glucagon, glucocorticoides, growth hormone, estrogen, artificial hormone, thyroid hormone and their combinations. Requirement 21: cell screening methods, including: (a) obtaining transplanted cells； (b) combining cells with the biological substance forming the gel to form a mixture； (c) optionally combining the mixture with one o
