FUSION PROTEIN COMPRISING A LIGAND BINDING DOMAIN OF VEGF AND PDGF

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专利权人:

ALLGENESIS BIOTHERAPEUTICS INC.;AP BIOSCIENCES, INC.

发明人:

WU, PEI TZU,HER, Jeng-Horng,CHEN, Huang-Tsu,ZEN, Kevin,LEOU, Jiun-Shyang,HSU, Ching-Hsuan

申请号：

SG11201705271Y

公开号：

SG11201705271YA

申请日:

2016.03.10

申请国别(地区):

SG

年份:

2017

代理人:

摘要：

Fusion proteins containing a PDGF binding portion, a VEGF binding portion, and an Fc antibody region are described. Also described are nucleic acids encoding the fusion proteins, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing clinical conditions characterized by abnormal angiogenesis, such as vascular permeability, edema or inflammation.

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