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FUSION PROTEIN COMPRISING A LIGAND BINDING DOMAIN OF VEGF AND PDGF
专利权人:
Allgenesis Biotherapeutics Inc.;AP Biosciences, Inc.
发明人:
Kevin ZEN,Pei-Tzu WU,Jeng-Horng HER,Huang-Tsu CHEN,Jiun-Shyang LEOU,Ching-Hsuan HSU
申请号:
US15542692
公开号:
US20170369552A1
申请日:
2016.03.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Fusion proteins containing a PDGF binding portion, a VEGF binding portion, and an Fc antibody region are described. Also described are nucleic acids encoding the fusion proteins, compositions comprising the fusion proteins, and methods of using the fusion proteins for treating or preventing clinical conditions characterized by abnormal angiogenesis, such as vascular permeability, edema or inflammation.
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