Isolated polypeptides of CD44 and uses thereof

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专利权人:

Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.

发明人:

Naor, David,Eshkar-Sebban, Lora,Amar, Keren-Or,Cohen, Shmuel

申请号：

AU2015291151

公开号：

AU2015291151B2

申请日:

2015.07.15

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.

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