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Isolated polypeptides of CD44 and uses thereof
专利权人:
Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
发明人:
Naor, David,Eshkar-Sebban, Lora,Amar, Keren-Or,Cohen, Shmuel
申请号:
AU2015291151
公开号:
AU2015291151B2
申请日:
2015.07.15
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.
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