Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
发明人:
David Naor,Lora Eshkar-Sebban,Keren-Or Amar,Shmuel Cohen
申请号：
US15324768
公开号：
US10611819B2
申请日:
2015.07.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.
