POLYPEPTIDES ISOLES DE CD44 ET UTILISATIONS ASSOCIEES

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专利权人:

YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.

发明人:

NAOR, DAVID,ESHKAR-SEBBAN, LORA,AMAR, KEREN-OR,COHEN, SHMUEL

申请号：

CA2951984

公开号：

CA2951984A1

申请日:

2015.07.15

申请国别(地区):

CA

年份:

2016

代理人:

摘要：

Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.

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