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POLYPEPTIDES ISOLES DE CD44 ET UTILISATIONS ASSOCIEES
专利权人:
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
发明人:
NAOR, DAVID,ESHKAR-SEBBAN, LORA,AMAR, KEREN-OR,COHEN, SHMUEL
申请号:
CA2951984
公开号:
CA2951984A1
申请日:
2015.07.15
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.
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