MERCK PATENT GESELLSCHAFT MIT BESCHRÄNKTER HAFTUNG
发明人:
HANS DR. BUCHSTALLER,DIETER PETER - DR. DORSCH
申请号：
ARP150101387
公开号：
AR100333A1
申请日:
2015.05.07
申请国别(地区):
AR
年份:
2016
代理人:
摘要：
Claim 1: compound of formula (1), wherein w represents the remaining part of a set of formulas (2), wherein * represents the binding point with other propylene； X represents or, 1. C. alternative (2) 1. I am absent； and mark AR or het； 1R1 means h, F, Cl, CN, ch832323,CF8323,CHF83222,it is life.R2 is h or ch8323；Ar for phenyl, not substituted or monkey,di- or trisubstituted with Hal, NO₂,CN A ORS (O) RN (R)COA, COOR³,CON (R)SO N (R)KelomboNR SO A NR CON (R) y 2Fo HetHet1 means anger, tienilo, pirrolilo, imidazolilo, pirazolilo, pirazolilo, pirazolilo, isoxazollo, oxadiazolilo, tiazolilo, triazolilo, tetrazolilo, piridio, piriminalo or piridazinilo, each substance has not been replaced or only desulfurized with Hal, no832222；Ar1,CN A ORN (R)CON (R)Het² and / u = O； Het² denotes furyl, thienyl, pyrrolyl, imidazolyl, pyrazolyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, triazolyl, tetrazolyl, pyridyl, pyrimidyl or pyridazinyl, each of which is unsubstituted or mono- or disubstituted with Hal, NO₂,Ar1,CN A ORN (R)And (R3) 83222y / u = O； AR1 is phenyl, not substituted or monkey,di- or trisubstituted with Hal, NO₂,CN A ORS (O) RN (R)COA, COOR³,CON (R)NR: cor and / or NR: so8322； a refers to untreated tar or resin, which consists of 1-8 C atoms, of which 1-2 HC and / or ch22832 non adjacent atoms can be replaced by N or O atoms, 1-7 H atoms can be replaced by F, Cl and / or Oh； R3 refers to untreated h or tar, which consists of 1, 2, 3 or 4 atoms； C. Hal refers to F, Cl, Br or I； m refers to 0, 1 or 2； n refers to 1 or 2； its salts, tautometers and stereoisomers have pharmaceutically acceptable properties, including mixtures of various proportions.Para el tratamiento de enfermedades tales como cáncer, enfermedades cardiovasculares, lesión del sistema nervioso central y diferentes formas de inflamación. Reivindicación 1: Compuestos de la fórmula (1) en donde W denota un resto del grupo de fórmulas (2) en donde * indica el punto de unión con el resto de propileno； X deno
