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COMPOUND, COMPOUND FOR USE IN THE TREATMENT OF A PATHOLOGICAL CONDITION, A PHARMACEUTICAL COMPOSITION AND A METHOD FOR PREPARING SAID COMPOUND
专利权人:
发明人:
申请号:
EP17165807.3
公开号:
EP3388430A1
申请日:
2017.04.10
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The invention concerns a compound, wherein the compound is a substance according to the following formula (I)wherein R1 is-SO3H, 1-methyl-4,5-dihydro-1H-imidazol-2-yl,wherein the ring A is a pyrrolidine, piperidine, morpholine, or imidazole residue or a substituted pyrrolidine, piperidine, morpholine, or imidazole residue, Q is -NH-, -NH-alkyl-, -O-, or -S- and R7 is -H, a substituted or non-substituted pyrrolidine, piperidine, morpholine, triazine, or imidazole residue, or a substituted or non-substituted alkylpyrrolidine, alkylpiperidine, alkylmorpholine, alkyltriazine, or alkylimidazole residue, alkyl, alkylester, alkenyl, alkenylester, alkynyl, alkynylester, aminoalkyl, cyanyl, -NO2, methylsulfonyl residue, or a substituted or non-substituted form of any of the following residues: cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, bicycloalkyl, bicycloalkylalkyl, bicycloalkenyl, bicycloalkenylalkyl, or another bicyclic residue, aryl, aminoaryl, heteroaryl, heteroaminoaryl, cyclyl, aminocyclyl, heterocyclyl, heteroaminocyclyl, aralkyl, aminoaralkyl, heterocycloalkyl, or heteroaminocycloalkyl,R2 is-H, -Cl, -Br, -CF3, -CH=CH2 or another alkenyl, -C=CH or another alkynyl, phenyl or substituted phenyl, triazolyl or another heteroaryl, substituted triazolyl or another substituted heteroaryl, a residue of 9-BBN (9-borabicyclo[3.3.1]nonane), OBBD (9-oxa-10-borabicyclo[3.3.2]decane), trifluoroborate, boronic acid, or an ester of boronic acid and pinacol, methyliminodiacetic acid (MIDA), catechol, pinane diol, ethylene glycol, or propane diol or another boronic acid ester,wherein the ring A is a pyrrolidine, piperidine, morpholine, or imidazole residue or a substituted pyrrolidine, piperidine, morpholine, or imidazole residue, Q is -NH-, -NH-alkyl-, -O-, or -S- and R7 is -H, a substituted or non-substituted pyrrolidine, piperidine, morpholine, triazine, or imidazole residue, or a substituted or non-substituted alkylpyrrolidine, alkylpiperidine, alkylmorpholine,
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