PINT KNOCKOUT MOUSE EXHIBITING A PREMATURE AGING-ASSOCIATED PHENOTYPE

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专利权人:

发明人:

申请号：

HK17112499.2

公开号：

HK1238673A

申请日:

2017.11.27

申请国别(地区):

HK

年份:

2018

代理人:

摘要：

Genetically modified non-human animals are provided that exhibit a functional lack of one or more lncRNAs. Methods and compositions for disrupting, deleting, and/or replacing lncRNA-encoding sequences are provided. Genetically modified mice that age prematurely are provided. Also provided are cells, tissues and embryos that are genetically modified to comprise a loss-of-function of one or more lncRNAs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/