CHEN, YOUNG, K,CO, ERICK WANG,GUNTUPALLI, PRASUNA,LAWSON, JOHN DAVID,NOTZ, WOLFGANG REINHARD LUDWIG,STAFFORD, JEFFREY A,TON-NU, HUONG-THU
申请号:
NZ58720709
公开号:
NZ587207A
申请日:
2009.01.30
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed herein are 7,8-dihydropyrido[4,3-d]pyrimidin compounds of the given formula wherein the substituents are as defined within the specification, processes for their preparation, as well as composition comprising said compounds. Said compounds are useful as inhibitors of heat shock protein 90 (HSP90) and as such are useful in the treatment of cancer, inflammation, inflammatory bowel disease, psoriasis, arthritis and transplant rejection.