Magnuson Steven R,Rawson Thomas E,Zak Mark E,Liu Wendy,Mendonca Rohan,Pastor Richard,Lyssikatos Joseph P,Siu Michael,Gibbons Paul,Zhou Aihe,Zhu Bing-Yan,Hanan Emily
申请号：
NZ71997210
公开号：
NZ719972A
申请日:
2010.07.02
申请国别(地区):
NZ
年份:
2018
代理人:
摘要：
Disclosed are pyrazolopyrimidine compounds of formula (I) and methods for their preparation. In particular the compound is N-(3-(3-chlorophenyl)-5-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. The compounds of formula (I) are Janus kinase (JAK) inhibitors, and useful for treating cancer, polycythaemia Vera, essential thrombocytosis, myelofibrosis, chronic myelogenous leukaemia (CML), rheumatoid arthritis, inflammatory bowel syndrome, Chron’s disease, psoriasis, contact dermatitis or delayed hypersensitivity reactions.
