Phillip Parsons,Silvia Trasciatti,Sergio Rosini,Michael Annis
申请号:
US13137325
公开号:
US20120015947A1
申请日:
2011.08.05
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound of formula (I):in which—X represents O or CH2R3 and R4 each independently represent hydrogen or C1-6 alkylp represent 0 or 1 andR represents a five- or six-membered saturated or unsaturated ring selected from:orR represents a five- or six-membered oxo-substituted unsaturated ring selected from:wherein R1 and R2 together represent an oxo group, or R1 and R2 each represent hydrogen, methoxy or ethoxy, or R1 and R2 together with the interjacent carbon atom represent a 1,3-dioxolane or 1,3-dioxane ring, attached via the 2 position and optionally bearing one or more methyl or ethyl groupsor a salt thereof, is suitable for the treatment of anxiety and depression.