NOVEL POLYPEPTIDES WITH IMPROVED PROTEOLYTIC STABILITY AND METHODS OF PREPARING AND USING SAME

• 收藏
• 分享

专利权人:

发明人:

KUMAR KRISHNA,MONTANARI VITTORIO,BEINBORN MARTIN,RAMAN VENKATA

申请号：

IN201817019138

公开号：

IN201817019138A

申请日:

2018.05.22

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The present invention includes methods of improving proteolytic stability of a polypeptide comprising alkylating at least one selected from the group consisting of a N-terminus amino group the NH group of the N-terminus first internal amide bond another primary amino group a thiol group and a thioether group within the polypeptide. The present invention further includes polypeptides incorporating such chemical modifications.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/